Cybercrime is a flourishing business, with many operators expanding into persistent cybercriminal enterprise. Deeply funded, the threat actors involved and their techniques, tactics and procedures (TTPs) are becoming ever more sophisticated. So much so that they are now operating as structured organizations with business units, affiliates and developers that are weaponizing zero-day attacks.  These groups continue to add to their ecosystem and their playbooks using ransomware extortion models, and destructive techniques as they target operational technology. This session will look at the modern threat landscape and the top threats that FortiGuard Labs tracks, observing how the modern cybercriminal enterprise operates as well as prominent APT groups. From there, we will take it to a global stage showcasing how we can fight back vs. cybercrime and work in partnership to move the needle. Existing efforts underway for disruption of cybercrime between private sector, law enforcement and industry will presented.